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Moreover, the residual error with the metabolite was 10.nine% and one.06 ng/mL for the proportional error and additive mistake, respectively. The fundamental goodness-of-suit plots for the ultimate design are proven in Figures three and ​and4.4. The diagnostic plots of the ultimate population PK design uncovered no systematic bias. The population

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Inside the realm of pharmacology, desmetramadol garnered consideration for its exceptional pharmacological profile. Researchers and healthcare professionals recognized its distinctive Qualities and utility. This recognition proved specially important in instances wherever tramadol's success was affected by specific variations in CYP2D6 enzyme e

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